Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Three-dimensional optical tomography: resolution in small-object imaging

Not Accessible

Your library or personal account may give you access

Abstract

Near-infrared (NIR) optical tomography can provide estimates of the internal distribution of optical absorption and transport scattering from boundary measurements of light propagation within biological tissue. Although this is a truly three-dimensional (3D) imaging problem, most research to date has concentrated on two-dimensional modeling and image reconstruction. More recently, 3D imaging algorithms are demonstrating better estimation of the light propagation within the imaging region and are providing the basis of more accurate image reconstruction algorithms. As 3D methods emerge, it will become increasingly important to evaluate their resolution, contrast, and localization of optical property heterogeneity. We present a concise study of 3D reconstructed resolution of a small, low-contrast, absorbing and scattering anomaly as it is placed in different locations within a cylindrical phantom. The object is an 8-mm-diameter cylinder, which represents a typical small target that needs to be resolved in NIR mammographic imaging. The best resolution and contrast is observed when the object is located near the periphery of the imaging region (12–22 mm from the edge) and is also positioned within the multiple measurement planes, with the most accurate results seen for the scatter image when the anomaly is at 17 mm from the edge. Furthermore, the accuracy of quantitative imaging is increased to almost 100% of the target values when a priori information regarding the internal structure of imaging domain is utilized.

© 2003 Optical Society of America

Full Article  |  PDF Article
More Like This
Multiwavelength three-dimensional near-infrared tomography of the breast: initial simulation, phantom, and clinical results

Hamid Dehghani, Brian W. Pogue, Steven P. Poplack, and Keith D. Paulsen
Appl. Opt. 42(1) 135-145 (2003)

Three-dimensional shape-based imaging of absorption perturbation for diffuse optical tomography

Misha E. Kilmer, Eric L. Miller, Alethea Barbaro, and David Boas
Appl. Opt. 42(16) 3129-3144 (2003)

Effects of refractive index on near-infrared tomography of the breast

Hamid Dehghani, Ben A. Brooksby, Brian W. Pogue, and Keith D. Paulsen
Appl. Opt. 44(10) 1870-1878 (2005)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (14)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (8)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved