Abstract

We have developed a methodology that can be used in reconstruction algorithms to quantify the optical coefficients and the geometrical cross section of a weakly abnormal optical target embedded in an otherwise homogeneous medium. This novel procedure uses different time-dependent point-spread functions to analyze the diffusive and absorptive contrasts obtained from time-of-flight measurements. Data obtained from time-resolved transillumination of a tissuelike phantom are used to test the accuracy of this new deconvolution methodology.

© 1998 Optical Society of America

Quantification by random walk of the optical parameters of nonlocalized abnormalities embedded within tissuelike phantoms

Victor Chernomordik, David Hattery, Amir H. Gandjbakhche, Antonio Pifferi, Paola Taroni, Alessandro Torricelli, Gianluca Valentini, and Rinaldo Cubeddu
Opt. Lett. 25(13) 951-953 (2000)

Absorptivity contrast in transillumination imaging of tissue abnormalities

A. H. Gandjbakhche, R. F. Bonner, R. Nossal, and G. H. Weiss
Appl. Opt. 35(10) 1767-1774 (1996)

Experimental test of a perturbation model for time-resolved imaging in diffusive media

Lorenzo Spinelli, Alessandro Torricelli, Antonio Pifferi, Paola Taroni, and Rinaldo Cubeddu
Appl. Opt. 42(16) 3145-3153 (2003)

Depth dependence of estimated optical properties of a scattering inclusion by time-resolved contrast functions

Rosario Esposito, Sergio De Nicola, Marco Brambilla, Antonio Pifferi, Lorenzo Spinelli, and Maria Lepore
Opt. Express 16(22) 17667-17681 (2008)

Imaging very-low-contrast objects in breastlike scattering media with a time-resolved method

David J. Hall, Jeremy C. Hebden, and David T. Delpy
Appl. Opt. 36(28) 7270-7276 (1997)